Vol. 1 Núm. 0015 (2020): Protocol: Kounis syndrome secondary to heparin in a newborn with hypoplastic left heart.

RESUMEN: Kounis syndrome (KS) is an acute coronary syndrome (ACS) described in relationship with drugs or stents. KS was suspected in a full-term newborn who underwent a Rashkind-atrioseptostomy and stenting that periodically developed episodes of ACS. Skin test with nickel and titanium were performed being negatives. Basophil activation (BAT) and lymphocyte transformation (LTT) tests were performed for the suspected drugs. Non-responder basophils in BAT and a positive LTT for heparin were found. A new dose of heparin was administered by error, after which a new ACS was developed. We described the first report of KS by drug in a newborn.

Authors: Paloma López Ortego¹, Javier Queiruga Parada², Luz Yadira Bravo Gallego³, Carmen Gómez Traseira⁴, Viviana Arreo⁵, Juvenal Rey⁶, Amelia Rodríguez Mariblanca², Enrique Seco Meseguer², Miguel González-Muñoz^4*, Elena Ramírez^2*

Year: 2020 Volume: 1 Issue: 1 Number: e0015